I also moved the rear sight to the right to compensate for shooting left and low. However, I doubt that it is the sight install that is the entire problem. For me it the problem seems to be how I shoot offhand (no rest).
When I first started shooting semi-autos about a couple of years ago, I used to shoot VERY LEFT and VERY LOW. Now with much study and dry practice, I hold the gun and handle the trigger differently than I used to, and they are hitting closer to center with more consistency.
In addition to proper trigger pull and proper grip, an important thing for me is that I must strive to allow my arm/wrist to point the pistol in what is a natural arm/wrist extension. Because of my stance and shoulder width, sometimes I catch myself bending my wrist slightly to the right so that I don't have to bend my neck so far to the right to get sight alignment. When that happens, I start shooting very badly.
To overcome that problem, I close my eyes, point the gun, then open my eyes to find the natural position of my arm and wrist angle. Then I move my head to the right to get sight alignment. Under no circumstances do I allow my wrist to bend right to come to sight alignment. When I do this, my natural arm/wrist alignment is very straight, and my shots tend to move consistently to the right/up (and center of target).
I'm interested to hear if this helps anyone else also. It was a discovery that I figured lots of you guys already knew, so I never brought it up before.