Personal opinion here, so take it with $.02 worth of salt... Is that how the saying goes? No? Screw it...
Considering that the magazine is the most likely component in an autopistol to be damaged, ejected, or otherwise rendered unable to do its job of feeding ammunition to the pistol, I view magazine disconnects to be a liability, rather than a benefit. Have a magazine that's been barely bumped out of it's locked position because you were traveling in a car? Hope you don't need it in a gunfight! I've had my magazine partially ejected from my XD45c, but thankfully it doesn't have a magazine disconnect and I didn't need it for self-defense prior to noticing the problem.
The manual safety can and does have a viable use, and some will not use a pistol that lacks it. Hopefully those with safety-equipped pistols train in ensuring the safety is off when it needs to be so they don't wind up in a situation wondering why the pistol isn't firing it when they need it to.
Every pistol has shortcomings that need to be evaluated, and the shooter must train to ensure these shortcomings don't get them killed. Hopefully we are all making the right choices for our individual needs and train appropriately.